From the publisher's website:
A power struggle at the beginning of an atomic age. A revolutionary new technology. Who will use it to build the deadliest arsenal and become the world's dominant superpower?
The Manhattan Project is a low-luck, mostly open information efficiency game in which players compete to build and operate the most effective atomic bomb program. Players do not "nuke" each other, but conventional air strikes are allowed against facilities.
The game features worker placement with a twist; There are no rounds and no end-of-round administration. Players retrieve their workers when they choose to or are forced to (by running out).
An espionage action allows a player to activate and block an opponent's building, representing technology theft and sabotage.